3FLS

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 3FLS_A

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GENERAL

TITLE

P38 KINASE CRYSTAL STRUCTURE IN COMPLEX WITH 6-(2,4-DIFLUORO-PHENOXY)- 2-((R)-2-METHANESULFONYL-1-METHYL-ETHYLAMINO)-8-METHYL-8H-PYRIDO[2,3- D]PYRIMIDIN-7-ONE

DATE LAST MODIFIED

Feb 21, 2024

RELEASE

Dec 22, 2009

CLASSIFICATION

SIGNALING PROTEIN, TRANSFERASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

2.3

RESOLUTION RANGE LOW

PUBMED ID

DOI

PDBe

3FLS

LIGANDS

174305

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	Q16539	CSBP, CSBP1, CSBP2, CSPB1, MAPK14, MXI2	ESCHERICHIA COLI	HUMAN	MITOGEN-ACTIVATED PROTEIN KINASE P38 ALPHA, MAP KI ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402