3N2U

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 3N2U_A

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GENERAL

TITLE

CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN MMP12 COMPLEXED WITH THE INHIBITOR N-HYDROXY-2-(4-METHOXY-N(2-(3,4,5-TRIHYDROXY-6- (HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-2-YLOXY)ETHYL)PHENYLSULFONAMIDO) ACETAMIDE

DATE LAST MODIFIED

Sep 6, 2023

RELEASE

Nov 10, 2010

CLASSIFICATION

HYDROLASE/HYDROLASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

C 1 2 1

RESOLUTION RANGE HIGH

1.8

RESOLUTION RANGE LOW

30.22

PUBMED ID

20965620

DOI

10.1016/J.EJMECH.2010.09.057

PDBe

LIGANDS

2838553 , 354100 , 23

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P39900	MMP12, HME	ESCHERICHIA COLI	HUMAN	MME, MATRIX METALLOPROTEINASE-12, MMP-12, MACROPHA ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402