3NDM

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 3NDM_1

Bioassembly 3NDM_2

Chain 3NDM_A

Chain 3NDM_B

Chain 3NDM_C

Chain 3NDM_D

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GENERAL

TITLE

CRYSTAL STRUCTURE OF RHO-ASSOCIATED PROTEIN KINASE (ROCK1) WITH A POTENT ISOQUINOLONE DERIVATIVE

DATE LAST MODIFIED

Feb 21, 2024

RELEASE

Dec 8, 2010

CLASSIFICATION

TRANSFERASE/TRANSFERASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

C 1 2 1

RESOLUTION RANGE HIGH

3.3

RESOLUTION RANGE LOW

46.95

PUBMED ID

DOI

10.1016/J.BMCL.2010.04.069

PDBe

LIGANDS

Target Protein	Gene	Expression System	Organism	Synonims	Actions
Q13464	--	SPODOPTERA FRUGIPERDA	HUMAN	ROCK1	Mutations
Q13464	--	SPODOPTERA FRUGIPERDA	HUMAN	ROCK1	Mutations
Q13464	--	SPODOPTERA FRUGIPERDA	HUMAN	ROCK1	Mutations
Q13464	--	SPODOPTERA FRUGIPERDA	HUMAN	ROCK1	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402