3S3V

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 3S3V_2

Chain 3S3V_A

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GENERAL

TITLE

HUMAN DIHYDROFOLATE REDUCTASE Q35K/N64F DOUBLE MUTANT BINARY COMPLEX WITH TRIMETHOPRIM

DATE LAST MODIFIED

Feb 28, 2024

RELEASE

Sep 28, 2011

CLASSIFICATION

OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

H 3

RESOLUTION RANGE HIGH

1.53

RESOLUTION RANGE LOW

53.68

PUBMED ID

DOI

10.1016/J.JSB.2011.06.001

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P00374	DHFR, PDS5	ESCHERICHIA COLI	HUMAN	--	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402