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GENERAL
TITLE
CRYSTAL STRUCTURE OF P38A MITOGEN-ACTIVATED PROTEIN KINASE IN COMPLEX WITH A TRIAZOLOPYRIDAZINONE INHIBITOR
DATE LAST MODIFIED
Feb 28, 2024
RELEASE
Aug 29, 2012
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.15
RESOLUTION RANGE LOW
30
PUBMED ID
DOI
10.1016/J.BMCL.2011.11.067
PDBe
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q16539 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2 ESCHERICHIA COLI HUMAN
MAP KINASE 14, MAPK 14, CYTOKINE SUPPRESSIVE ANTI- ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402