3V5L

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 3V5L_5

Bioassembly 3V5L_6

Chain 3V5L_A

Chain 3V5L_B

Chain 3V5L_C

Chain 3V5L_D

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GENERAL

TITLE

CRYSTAL STRUCTURE OF INTERLEUKIN-2 INDUCIBLE T-CELL KINASE ITK CATALYTIC DOMAIN WITH THIENOPYRAZOLYLINDOLE INHIBITOR 542

DATE LAST MODIFIED

Sep 13, 2023

RELEASE

May 2, 2012

CLASSIFICATION

TRANSFERASE/TRANSFERASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 21 1

RESOLUTION RANGE HIGH

1.86

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1016/J.BMCL.2012.03.016

PDBe

LIGANDS

Target Protein	Gene	Expression System	Organism	Synonims	Actions
Q08881	ITK, EMT, LYK	SPODOPTERA FRUGIPERDA	HUMAN	INTERLEUKIN-2-INDUCIBLE T CELL KINASE, IL-2-INDUCI ...	Mutations
Q08881	ITK, EMT, LYK	SPODOPTERA FRUGIPERDA	HUMAN	INTERLEUKIN-2-INDUCIBLE T CELL KINASE, IL-2-INDUCI ...	Mutations
Q08881	ITK, EMT, LYK	SPODOPTERA FRUGIPERDA	HUMAN	INTERLEUKIN-2-INDUCIBLE T CELL KINASE, IL-2-INDUCI ...	Mutations
Q08881	ITK, EMT, LYK	SPODOPTERA FRUGIPERDA	HUMAN	INTERLEUKIN-2-INDUCIBLE T CELL KINASE, IL-2-INDUCI ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402