4A55 logo

4A55

3D Structure View

Loading...

More Info

GENERAL
TITLE
CRYSTAL STRUCTURE OF P110ALPHA IN COMPLEX WITH ISH2 OF P85ALPHA AND THE INHIBITOR PIK-108
DATE LAST MODIFIED
Aug 29, 2012
RELEASE
Dec 28, 2011
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
I 2 2 2
RESOLUTION RANGE HIGH
3.5
RESOLUTION RANGE LOW
123.41
PUBMED ID
DOI
10.1038/ONC.2011.532
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P42337 -- SPODOPTERA FRUGIPERDA HOUSE MOUSE
PI3-KINASE SUBUNIT ALPHA, PI3K-ALPHA, PI3KALPHA,PT ...
Mutations
P27986 -- SPODOPTERA FRUGIPERDA HUMAN
PI3-KINASE REGULATORY SUBUNIT ALPHA, PI3K REGULATO ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402