4ANS

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 4ANS_A

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GENERAL

TITLE

STRUCTURE OF L1196M,G1269A DOUBLE MUTANT ANAPLASTIC LYMPHOMA KINASE IN COMPLEX WITH CRIZOTINIB

DATE LAST MODIFIED

Dec 20, 2023

RELEASE

Mar 27, 2013

CLASSIFICATION

TRANSFERASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

1.84

RESOLUTION RANGE LOW

105.07

PUBMED ID

DOI

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	Q9UM73	--	SPODOPTERA FRUGIPERDA	HUMAN	ANAPLASTIC LYMPHOMA KINASE, CD246	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402