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GENERAL
TITLE
CRYSTAL STRUCTURE OF HIGH-AFFINITY VON WILLEBRAND FACTOR A1 DOMAIN WITH DISULFIDE MUTATION IN COMPLEX WITH HIGH AFFINITY GPIB ALPHA
DATE LAST MODIFIED
Mar 12, 2014
RELEASE
Jan 8, 2014
CLASSIFICATION
BLOOD CLOTTING
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.8
RESOLUTION RANGE LOW
48.3
PUBMED ID
DOI
10.1074/JBC.M113.511220
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P04275 -- ESCHERICHIA COLI HUMAN
VWF, VON WILLEBRAND ANTIGEN II, VON WILLEBRAND FAC ...
Mutations
P07359 -- HOMO SAPIENS HUMAN
GP-IB ALPHA, GPIB-ALPHA, GPIBA, GLYCOPROTEIN IBALP ...
Mutations
P04275 -- ESCHERICHIA COLI HUMAN
VWF, VON WILLEBRAND ANTIGEN II, VON WILLEBRAND FAC ...
Mutations
P07359 -- HOMO SAPIENS HUMAN
GP-IB ALPHA, GPIB-ALPHA, GPIBA, GLYCOPROTEIN IBALP ...
Mutations
P04275 -- ESCHERICHIA COLI HUMAN
VWF, VON WILLEBRAND ANTIGEN II, VON WILLEBRAND FAC ...
Mutations
P07359 -- HOMO SAPIENS HUMAN
GP-IB ALPHA, GPIB-ALPHA, GPIBA, GLYCOPROTEIN IBALP ...
Mutations
P04275 -- ESCHERICHIA COLI HUMAN
VWF, VON WILLEBRAND ANTIGEN II, VON WILLEBRAND FAC ...
Mutations
P07359 -- HOMO SAPIENS HUMAN
GP-IB ALPHA, GPIB-ALPHA, GPIBA, GLYCOPROTEIN IBALP ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402