4C2B

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 4C2B_1

Bioassembly 4C2B_2

Bioassembly 4C2B_3

Bioassembly 4C2B_4

Chain 4C2B_A

Chain 4C2B_B

Chain 4C2B_C

Chain 4C2B_D

Chain 4C2B_E

Chain 4C2B_F

Chain 4C2B_G

Chain 4C2B_H

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GENERAL

TITLE

CRYSTAL STRUCTURE OF HIGH-AFFINITY VON WILLEBRAND FACTOR A1 DOMAIN WITH DISULFIDE MUTATION IN COMPLEX WITH HIGH AFFINITY GPIB ALPHA

DATE LAST MODIFIED

Mar 12, 2014

RELEASE

Jan 8, 2014

CLASSIFICATION

BLOOD CLOTTING

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 21 1

RESOLUTION RANGE HIGH

2.8

RESOLUTION RANGE LOW

48.3

PUBMED ID

24391089

DOI

10.1074/JBC.M113.511220

PDBe

4C2B

LIGANDS

10130 , 1514 , 465

Chains

Target Protein	Gene	Expression System	Organism	Synonims	Actions
P04275	--	ESCHERICHIA COLI	HUMAN	VWF, VON WILLEBRAND ANTIGEN II, VON WILLEBRAND FAC ...	Mutations
P07359	--	HOMO SAPIENS	HUMAN	GP-IB ALPHA, GPIB-ALPHA, GPIBA, GLYCOPROTEIN IBALP ...	Mutations
P04275	--	ESCHERICHIA COLI	HUMAN	VWF, VON WILLEBRAND ANTIGEN II, VON WILLEBRAND FAC ...	Mutations
P07359	--	HOMO SAPIENS	HUMAN	GP-IB ALPHA, GPIB-ALPHA, GPIBA, GLYCOPROTEIN IBALP ...	Mutations
P04275	--	ESCHERICHIA COLI	HUMAN	VWF, VON WILLEBRAND ANTIGEN II, VON WILLEBRAND FAC ...	Mutations
P07359	--	HOMO SAPIENS	HUMAN	GP-IB ALPHA, GPIB-ALPHA, GPIBA, GLYCOPROTEIN IBALP ...	Mutations
P04275	--	ESCHERICHIA COLI	HUMAN	VWF, VON WILLEBRAND ANTIGEN II, VON WILLEBRAND FAC ...	Mutations
P07359	--	HOMO SAPIENS	HUMAN	GP-IB ALPHA, GPIB-ALPHA, GPIBA, GLYCOPROTEIN IBALP ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402