4FC0

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 4FC0_1

Chain 4FC0_A

Chain 4FC0_B

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GENERAL

TITLE

CRYSTAL STRUCTURE OF HUMAN KINASE DOMAIN OF B-RAF WITH A DFG-OUT INHIBITOR

DATE LAST MODIFIED

RELEASE

Jan 8, 2014

CLASSIFICATION

TRANSFERASE/TRANSFERASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 41 21 2

RESOLUTION RANGE HIGH

2.95

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1016/J.BMC.2012.07.032

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P15056	BRAF, BRAF1, P94, RAFB1, V-RAF MURINE SARCOMA VIRAL ONCOGENE	SPODOPTERA FRUGIPERDA	HUMAN	PROTO-ONCOGENE B-RAF, P94, V-RAF MURINE SARCOMA VI ...	Mutations
	P15056	BRAF, BRAF1, P94, RAFB1, V-RAF MURINE SARCOMA VIRAL ONCOGENE	SPODOPTERA FRUGIPERDA	HUMAN	PROTO-ONCOGENE B-RAF, P94, V-RAF MURINE SARCOMA VI ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402