4FHB

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 4FHB_1

Chain 4FHB_A

Chain 4FHB_D

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GENERAL

TITLE

ENHANCING DHFR CATALYSIS BY BINDING OF AN ALLOSTERIC REGULATOR NANOBODY (NB179)

DATE LAST MODIFIED

Nov 15, 2017

RELEASE

Apr 24, 2013

CLASSIFICATION

OXIDOREDUCTASE/PROTEIN BINDING

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 61 2 2

RESOLUTION RANGE HIGH

2.8

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1016/J.BBAPAP.2013.07.010

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P0ABQ4	FOLA, TMRA, B0048, JW0047	ESCHERICHIA COLI	ESCHERICHIA COLI	--	Mutations
		--	ESCHERICHIA COLI	LAMA GLAMA	--

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402