4FSL

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 4FSL_A

Chain 4FSL_B

Chain 4FSL_D

Chain 4FSL_E

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GENERAL

TITLE

CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME 1 (BACE-DB-MUT) COMPLEX WITH N-(N-(4- ACETAMIDO-3-CHLORO-5-METHYLBENZYL) CARBAMIMIDOYL)-3-(4- METHOXYPHENYL)-5-METHYL-4-ISOTHIAZOLECARBOXAMIDE

DATE LAST MODIFIED

Jul 17, 2019

RELEASE

Oct 10, 2012

CLASSIFICATION

HYDROLASE/INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 21 1

RESOLUTION RANGE HIGH

2.5

RESOLUTION RANGE LOW

PUBMED ID

23030502

DOI

10.1021/JM300931Y

PDBe

LIGANDS

2887868 , 16

Chains

Target Protein	Gene	Expression System	Organism	Synonims	Actions
P56817	BACE1, BACE, KIAA1149	ESCHERICHIA COLI	HUMAN	ASPARTYL PROTEASE 2, ASP2, ASP 2, BETA-SITE AMYLOI ...	Mutations
P56817	BACE1, BACE, KIAA1149	ESCHERICHIA COLI	HUMAN	ASPARTYL PROTEASE 2, ASP2, ASP 2, BETA-SITE AMYLOI ...	Mutations
P56817	BACE1, BACE, KIAA1149	ESCHERICHIA COLI	HUMAN	ASPARTYL PROTEASE 2, ASP2, ASP 2, BETA-SITE AMYLOI ...	Mutations
P56817	BACE1, BACE, KIAA1149	ESCHERICHIA COLI	HUMAN	ASPARTYL PROTEASE 2, ASP2, ASP 2, BETA-SITE AMYLOI ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402