4FZB

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 4FZB_1

Bioassembly 4FZB_2

Bioassembly 4FZB_3

Bioassembly 4FZB_4

Chain 4FZB_A

Chain 4FZB_B

Chain 4FZB_C

Chain 4FZB_D

Chain 4FZB_E

Chain 4FZB_F

Chain 4FZB_G

Chain 4FZB_H

Chain 4FZB_I

Chain 4FZB_J

Chain 4FZB_K

Chain 4FZB_L

Chain 4FZB_M

Chain 4FZB_N

Chain 4FZB_O

Chain 4FZB_P

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GENERAL

TITLE

STRUCTURE OF THYMIDYLATE SYNTHASE THYX COMPLEXED TO A NEW INHIBITOR

DATE LAST MODIFIED

Sep 13, 2023

RELEASE

May 22, 2013

CLASSIFICATION

TRANSFERASE/TRANSFERASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1

RESOLUTION RANGE HIGH

2.59

RESOLUTION RANGE LOW

PUBMED ID

23155486

DOI

10.1098/RSOB.120120

PDBe

4FZB

LIGANDS

1337518 , 173 , 963386

Chains

Target Protein	Gene	Expression System	Organism	Synonims	Actions
O41156	A674R, THYX	ESCHERICHIA COLI	PBCV-1	TS, TSASE	Mutations
O41156	A674R, THYX	ESCHERICHIA COLI	PBCV-1	TS, TSASE	Mutations
O41156	A674R, THYX	ESCHERICHIA COLI	PBCV-1	TS, TSASE	Mutations
O41156	A674R, THYX	ESCHERICHIA COLI	PBCV-1	TS, TSASE	Mutations
O41156	A674R, THYX	ESCHERICHIA COLI	PBCV-1	TS, TSASE	Mutations
O41156	A674R, THYX	ESCHERICHIA COLI	PBCV-1	TS, TSASE	Mutations
O41156	A674R, THYX	ESCHERICHIA COLI	PBCV-1	TS, TSASE	Mutations
O41156	A674R, THYX	ESCHERICHIA COLI	PBCV-1	TS, TSASE	Mutations
O41156	A674R, THYX	ESCHERICHIA COLI	PBCV-1	TS, TSASE	Mutations
O41156	A674R, THYX	ESCHERICHIA COLI	PBCV-1	TS, TSASE	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402