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GENERAL
TITLE
STRUCTURE OF AN RBX1-UBC12~NEDD8-CUL1-DCN1 COMPLEX: A RING-E3- E2~UBIQUITIN-LIKE PROTEIN-SUBSTRATE INTERMEDIATE TRAPPED IN ACTION
DATE LAST MODIFIED
Jan 29, 2020
RELEASE
Jul 2, 2014
CLASSIFICATION
LIGASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
3.1
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1016/J.CELL.2014.04.037
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q13616 CUL1 ESCHERICHIA COLI HUMAN
CUL-1
Mutations
P62877 RBX1, RNF75, ROC1 ESCHERICHIA COLI HUMAN
PROTEIN ZYP,RING FINGER PROTEIN 75,RING-BOX PROTEI ...
Mutations
Q13616 CUL1 ESCHERICHIA COLI HUMAN
CUL-1
Mutations
P62877 RBX1, RNF75, ROC1 ESCHERICHIA COLI HUMAN
PROTEIN ZYP,RING FINGER PROTEIN 75,RING-BOX PROTEI ...
Mutations
Q96GG9 DCUN1D1, DCUN1L1, RP42, SCCRO ESCHERICHIA COLI HUMAN
DCUN1 DOMAIN-CONTAINING PROTEIN 1,DEFECTIVE IN CUL ...
Mutations
Q96GG9 DCUN1D1, DCUN1L1, RP42, SCCRO ESCHERICHIA COLI HUMAN
DCUN1 DOMAIN-CONTAINING PROTEIN 1,DEFECTIVE IN CUL ...
Mutations
P61081 UBE2M, UBC12 TRICHOPLUSIA NI HUMAN
NEDD8 CARRIER PROTEIN,NEDD8 PROTEIN LIGASE,UBIQUIT ...
Mutations
Q15843 NEDD8 ESCHERICHIA COLI HUMAN
NEDDYLIN,NEURAL PRECURSOR CELL EXPRESSED DEVELOPME ...
Mutations
P61081 UBE2M, UBC12 TRICHOPLUSIA NI HUMAN
NEDD8 CARRIER PROTEIN,NEDD8 PROTEIN LIGASE,UBIQUIT ...
Mutations
Q15843 NEDD8 ESCHERICHIA COLI HUMAN
NEDDYLIN,NEURAL PRECURSOR CELL EXPRESSED DEVELOPME ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402