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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN ADAMTS-4 IN COMPLEX WITH INHIBITOR (COMPOUND 1, 2-(4-CHLOROPHENOXY)-N-{[(4R)-4-METHYL-2,5- DIOXOIMIDAZOLIDIN-4-YL]METHYL} ACETAMIDE)
DATE LAST MODIFIED
Sep 27, 2017
RELEASE
Dec 10, 2014
CLASSIFICATION
HYDROLASE/HYDROLASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.17
RESOLUTION RANGE LOW
13.72
PUBMED ID
DOI
10.1021/JM501522N

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
O75173 ADAMTS4, KIAA0688, UNQ769/PRO1563 HOMO SAPIENS HUMAN
ADAMTS-4,ADMP-1,AGGRECANASE-1
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402