4XUF

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 4XUF_A

Chain 4XUF_B

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GENERAL

TITLE

CRYSTAL STRUCTURE OF THE FLT3 KINASE DOMAIN BOUND TO THE INHIBITOR QUIZARTINIB (AC220)

DATE LAST MODIFIED

Sep 27, 2023

RELEASE

Apr 15, 2015

CLASSIFICATION

TRANSFERASE/TRANSFERASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

3.2

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1371/JOURNAL.PONE.0121177

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P36888	FLT3, CD135, FLK2, STK1	UNIDENTIFIED BACULOVIRUS	HUMAN	FL CYTOKINE RECEPTOR,FETAL LIVER KINASE-2,FLK-2,FM ...	Mutations
	P36888	FLT3, CD135, FLK2, STK1	UNIDENTIFIED BACULOVIRUS	HUMAN	FL CYTOKINE RECEPTOR,FETAL LIVER KINASE-2,FLK-2,FM ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402