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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN PHOSPHORYLATED IRE1ALPHA IN COMPLEX WITH A TYPE III KINASE INHIBITOR (GSK2850163A)
DATE LAST MODIFIED
Sep 27, 2023
RELEASE
Nov 11, 2015
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 2
RESOLUTION RANGE HIGH
2.45
RESOLUTION RANGE LOW
29.182
PUBMED ID
DOI
10.1124/MOL.115.100917
PDBe
--
LIGANDS
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| O75460 | ERN1, IRE1 | SPODOPTERA FRUGIPERDA | HUMAN |
ENDOPLASMIC RETICULUM-TO-NUCLEUS SIGNALING 1,INOSI ...
| Mutations | |
| O75460 | ERN1, IRE1 | SPODOPTERA FRUGIPERDA | HUMAN |
ENDOPLASMIC RETICULUM-TO-NUCLEUS SIGNALING 1,INOSI ...
| Mutations | |
| O75460 | ERN1, IRE1 | SPODOPTERA FRUGIPERDA | HUMAN |
ENDOPLASMIC RETICULUM-TO-NUCLEUS SIGNALING 1,INOSI ...
| Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402