5IXS

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 5IXS_1

Chain 5IXS_A

Chain 5IXS_B

Chain 5IXS_C

Chain 5IXS_D

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GENERAL

TITLE

LACTATE DEHYDROGENASE IN COMPLEX WITH HYDROXYLACTAM INHIBITOR COMPOUND 9: (6R)-3-[(2-CHLOROPHENYL)SULFANYL]-4-HYDROXY-6-(3-HYDROXYPHENYL)-6- (THIOPHEN-3-YL)-5,6-DIHYDROPYRIDIN-2(1H)-ONE

DATE LAST MODIFIED

Sep 27, 2023

RELEASE

Sep 14, 2016

CLASSIFICATION

OXIREDUCTASE/OXIREDUCTASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 21 1

RESOLUTION RANGE HIGH

2.05

RESOLUTION RANGE LOW

37.8

PUBMED ID

27774125

DOI

10.1021/ACSMEDCHEMLETT.6B00190

PDBe

5IXS

LIGANDS

2849173 , 52348 , 901092 , 465 , 2950674

Chains

Target Protein	Gene	Expression System	Organism	Synonims	Actions
P00338	LDHA, PIG19	ESCHERICHIA COLI	HUMAN	LDH-A,CELL PROLIFERATION-INDUCING GENE 19 PROTEIN, ...	Mutations
P00338	LDHA, PIG19	ESCHERICHIA COLI	HUMAN	LDH-A,CELL PROLIFERATION-INDUCING GENE 19 PROTEIN, ...	Mutations
P00338	LDHA, PIG19	ESCHERICHIA COLI	HUMAN	LDH-A,CELL PROLIFERATION-INDUCING GENE 19 PROTEIN, ...	Mutations
P00338	LDHA, PIG19	ESCHERICHIA COLI	HUMAN	LDH-A,CELL PROLIFERATION-INDUCING GENE 19 PROTEIN, ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402