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3D Structure View

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GENERAL
TITLE
SELECTIVE INHIBITION OF AUTOTAXIN IS EFFECTIVE IN MOUSE MODELS OF LIVER FIBROSIS
DATE LAST MODIFIED
Jul 29, 2020
RELEASE
Nov 9, 2016
CLASSIFICATION
HYDROLASE/HYDROLASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
2.59
RESOLUTION RANGE LOW
65.84
PUBMED ID
DOI
10.1124/JPET.116.237156

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q13822 ENPP2, ATX, PDNP2 SPODOPTERA FRUGIPERDA HUMAN
E-NPP 2,AUTOTAXIN,EXTRACELLULAR LYSOPHOSPHOLIPASE ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402