5KXA

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 5KXA_A

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GENERAL

TITLE

SELECTIVE INHIBITION OF AUTOTAXIN IS EFFECTIVE IN MOUSE MODELS OF LIVER FIBROSIS

DATE LAST MODIFIED

Jul 29, 2020

RELEASE

Nov 9, 2016

CLASSIFICATION

HYDROLASE/HYDROLASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1

RESOLUTION RANGE HIGH

2.59

RESOLUTION RANGE LOW

65.84

PUBMED ID

DOI

10.1124/JPET.116.237156

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	Q13822	ENPP2, ATX, PDNP2	SPODOPTERA FRUGIPERDA	HUMAN	E-NPP 2,AUTOTAXIN,EXTRACELLULAR LYSOPHOSPHOLIPASE ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402