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GENERAL
TITLE
FACTOR VIIA IN COMPLEX WITH THE INHIBITOR 1-[(2R,15R)-2-[(1-AMINO-4- FLUOROISOQUINOLIN-6-YL)AMINO]-4,15,17-TRIMETHYL-3,12-DIOXO-13-OXA-4, 11-DIAZATRICYCLO[14.2.2.1~6,10~]HENICOSA-1(18),6(21),7,9,16,19- HEXAEN-7-YL]CYCLOHEXANE-1-CARBOXYLIC ACID
DATE LAST MODIFIED
Oct 12, 2016
RELEASE
Sep 28, 2016
CLASSIFICATION
HYDROLASE/HYDROLASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 41 21 2
RESOLUTION RANGE HIGH
1.79
RESOLUTION RANGE LOW
94.04
PUBMED ID
DOI
10.1016/J.BMCL.2016.08.088

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P08709 F7 CRICETINAE HUMAN
PROCONVERTIN,SERUM PROTHROMBIN CONVERSION ACCELERA ...
Mutations
P08709 F7 CRICETINAE HUMAN
PROCONVERTIN,SERUM PROTHROMBIN CONVERSION ACCELERA ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402