5L5S

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 5L5S_A

Chain 5L5S_B

Chain 5L5S_C

Chain 5L5S_D

Chain 5L5S_E

Chain 5L5S_F

Chain 5L5S_G

Chain 5L5S_H

Chain 5L5S_I

Chain 5L5S_J

Chain 5L5S_K

Chain 5L5S_L

Chain 5L5S_M

Chain 5L5S_N

Chain 5L5S_O

Chain 5L5S_P

Chain 5L5S_Q

Chain 5L5S_R

Chain 5L5S_S

Chain 5L5S_T

Chain 5L5S_U

Chain 5L5S_V

Chain 5L5S_W

Chain 5L5S_X

Chain 5L5S_Y

Chain 5L5S_Z

Chain 5L5S_a

Chain 5L5S_b

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GENERAL

TITLE

YEAST 20S PROTEASOME WITH HUMAN BETA5I (1-138; V31M) AND HUMAN BETA6 (97-111; 118-133) IN COMPLEX WITH PR-924

DATE LAST MODIFIED

Dec 14, 2016

RELEASE

Nov 9, 2016

CLASSIFICATION

HYDROLASE/HYDROLASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 21 1

RESOLUTION RANGE HIGH

2.6

RESOLUTION RANGE LOW

PUBMED ID

27789522

DOI

10.15252/EMBJ.201695222

PDBe

5L5S

LIGANDS

2954111 , 18 , 2838552

Chains

Target Protein	Gene	Expression System	Organism	Synonims	Actions
P23639	--	--	BAKER'S YEAST	MACROPAIN SUBUNIT Y7,MULTICATALYTIC ENDOPEPTIDASE ...	Mutations
P23638	--	--	BAKER'S YEAST	MACROPAIN SUBUNIT Y13,MULTICATALYTIC ENDOPEPTIDASE ...	Mutations
P40303	--	--	BAKER'S YEAST	MACROPAIN SUBUNIT PRE6,MULTICATALYTIC ENDOPEPTIDAS ...	Mutations
P32379	--	--	BAKER'S YEAST	MACROPAIN SUBUNIT PUP2,MULTICATALYTIC ENDOPEPTIDAS ...	Mutations
P40302	--	--	BAKER'S YEAST	MACROPAIN SUBUNIT PRE5,MULTICATALYTIC ENDOPEPTIDAS ...	Mutations
P21242	--	--	BAKER'S YEAST	MACROPAIN SUBUNIT C1,MULTICATALYTIC ENDOPEPTIDASE ...	Mutations
P21243	--	--	BAKER'S YEAST	MACROPAIN SUBUNIT C7-ALPHA,MULTICATALYTIC ENDOPEPT ...	Mutations
P25043	--	--	BAKER'S YEAST	MACROPAIN SUBUNIT PUP1,MULTICATALYTIC ENDOPEPTIDAS ...	Mutations
P25451	--	--	BAKER'S YEAST	MACROPAIN SUBUNIT PUP3,MULTICATALYTIC ENDOPEPTIDAS ...	Mutations
P22141	--	--	BAKER'S YEAST	MACROPAIN SUBUNIT C11,MULTICATALYTIC ENDOPEPTIDASE ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402