5LOF

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 5LOF_A

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GENERAL

TITLE

CRYSTAL STRUCTURE OF THE MBP-MCL1 COMPLEX WITH HIGHLY SELECTIVE AND POTENT INHIBITOR OF MCL1

DATE LAST MODIFIED

Jul 29, 2020

RELEASE

Oct 26, 2016

CLASSIFICATION

APOPTOSIS/INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 2

RESOLUTION RANGE HIGH

2.17

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1038/NATURE19830

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	Q07820	MALE, Z5632, ECS5017, MCL1, BCL2L3	ESCHERICHIA COLI	HUMAN	MBP,MMBP,MALTODEXTRIN-BINDING PROTEIN,BCL-2-LIKE P ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402