5O1S

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 5O1S_A

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GENERAL

TITLE

DIMETHYL FUMARATE IS AN ALLOSTERIC COVALENT INHIBITOR OF THE P90 RIBOSOMAL S6 KINASES

DATE LAST MODIFIED

Oct 31, 2018

RELEASE

May 30, 2018

CLASSIFICATION

TRANSFERASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 41 21 2

RESOLUTION RANGE HIGH

1.9

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1038/S41467-018-06787-W

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P18654	RPS6KA3, MAPKAPK1B, RPS6KA-RS1, RSK2	ESCHERICHIA COLI	MOUSE	S6K-ALPHA-3,90 KDA RIBOSOMAL PROTEIN S6 KINASE 3,P ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402