FEATURES

FAMILY

DESCRIPTION

Also known as CLCA1_HUMAN, CLCA1, CACC1. May be involved in mediating calcium-activated chloride conductance. May play critical roles in goblet cell metaplasia, mucus hypersecretion, cystic fibrosis and AHR. May be involved in the regulation of mucus production and/or secretion by goblet cells. Involved in the regulation of tissue inflammation in the innate immune response. May play a role as a tumor suppressor. Induces MUC5AC.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CLCA1

Calcium-activated chloride channel regulator 1

CLCA1

Molecular Synopsis