FEATURES

FAMILY

DESCRIPTION

Also known as TP4A3_HUMAN, PTP4A3, PRL3. Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II. Interacts with tubulin.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PTP4A3

Protein tyrosine phosphatase type IVA 3

PTP4A3

Molecular Synopsis