FEATURES

DESCRIPTION

Also known as AL1L1_HUMAN, ALDH1L1, FTHFD. Cytosolic 10-formyltetrahydrofolate dehydrogenase that catalyzes the NADP(+)-dependent conversion of 10-formyltetrahydrofolate to tetrahydrofolate and carbon dioxide (PubMed:19933275, PubMed:21238436). May also have an NADP(+)-dependent aldehyde dehydrogenase activity towards formaldehyde, acetaldehyde, propionaldehyde, and benzaldehyde (By similarity). Homotetramer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ALDH1L1

Cytosolic 10-formyltetrahydrofolate dehydrogenase

ALDH1L1

Molecular Synopsis