FEATURES

FAMILY

DESCRIPTION

Also known as LDHA_HUMAN, LDHA. Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+). Homotetramer (PubMed:11276087). Interacts with PTEN upstream reading frame protein MP31 (PubMed:33406399). Interacts with folliculin FLCN; the interaction is direct and inhibits enzymatic activity (PubMed:34381247).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

LDHA

L-lactate dehydrogenase A chain

LDHA

Molecular Synopsis