FEATURES

FAMILY

DESCRIPTION

Also known as KDPA_ECOLI, kdpA. Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm (PubMed:23930894, PubMed:2849541, PubMed:8499455). This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel (PubMed:7896809, PubMed:30478378, PubMed:34272288). The system is composed of three essential subunits: KdpA, KdpB and KdpC (PubMed:2849541, PubMed:9858692, PubMed:28636601, PubMed:30478378). The complex also contains KdpF, a small non-essential subunit (PubMed:10608856, PubMed:28636601, PubMed:30478378). The KdpFABC complex exists as a dimer above concentrations of 30-50 nM, whereas the complex exists as a functional monomer at lower concentrations (PubMed:18298081).

EXTERNAL LINKS

kdpA

Potassium-transporting ATPase potassium-binding subunit

kdpA

Molecular Synopsis