FEATURES

FAMILY

DESCRIPTION

Also known as APOA_HUMAN, LPA. Apo(a) is the main constituent of lipoprotein(a) (Lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1. Lp(a) may be a ligand for megalin/Gp 330. Disulfide-linked to apo-B100. Binds to fibronectin and decorin.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

LPA

Apolipoprotein(a)

LPA

Molecular Synopsis