FEATURES

FAMILY

DESCRIPTION

Also known as FA5_HUMAN, F5. Central regulator of hemostasis. It serves as a critical cofactor for the prothrombinase activity of factor Xa that results in the activation of prothrombin to thrombin. Factor Va, the activated form of factor V, is composed of a heavy chain and a light chain, non-covalently bound. The interaction between the two chains is calcium-dependent. Forms heterodimer with SERPINA5.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

F5

Coagulation factor V

F5

Molecular Synopsis