FEATURES

FAMILY

DESCRIPTION

Also known as T2FB_HUMAN, GTF2F2, RAP30. TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. Heterodimer of an alpha and a beta subunit. Interacts with HTATSF1 and GPBP1 (By similarity). Interacts with URI1. Interacts with GTF2B (via N-terminus); this interaction is inhibited in presence of GTF2F1 (PubMed:8504927, PubMed:8662660).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

GTF2F2

General transcription factor IIF subunit 2

GTF2F2

Molecular Synopsis