FEATURES

FAMILY

DESCRIPTION

Also known as OXDA_HUMAN, DAO, DAMOX. Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. Homodimer (PubMed:17088322, PubMed:18455394). Interacts with DAOA (PubMed:12364586).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

DAO

D-amino-acid oxidase

DAO

Molecular Synopsis