FEATURES

FAMILY

DESCRIPTION

Also known as 5NTD_HUMAN, NT5E, NT5, NTE. Catalyzes the hydrolysis of nucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside, with AMP being the preferred substrate (PubMed:21933152, PubMed:34403084, PubMed:24887587, PubMed:22997138, PubMed:23142347). Shows a preference for ribonucleotide monophosphates over their equivalent deoxyribose forms (PubMed:34403084). Other substrates include IMP, UMP, GMP, CMP, dAMP, dCMP, dTMP, NAD and NMN (PubMed:21933152, PubMed:34403084, PubMed:24887587, PubMed:22997138, PubMed:23142347). Homodimer.

Also known as 5NTD_HUMAN, NT5E, NT5, NTE. Catalyzes the hydrolysis of nucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside, with AMP being the preferred subst ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

NT5E

5'-nucleotidase

NT5E

Molecular Synopsis