FEATURES

DESCRIPTION

Also known as MSRE_HUMAN, MSR1, SCARA1. Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL) (PubMed:2251254). Isoform III does not internalize acetylated LDL (PubMed:9548586). Homotrimer (By similarity). Interacts with MYO18A (PubMed:25965346).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MSR1

Macrophage scavenger receptor types I and II

MSR1

Molecular Synopsis