FEATURES

FAMILY

DESCRIPTION

Also known as ANFC_HUMAN, NPPC, CNP2. Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation (By similarity). May also be vasoactive and natriuretic (PubMed:1672777). Acts by specifically binding and stimulating NPR2 to produce cGMP (PubMed:1672777, PubMed:21098034). Binds the clearance receptor NPR3 (PubMed:11533490).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

NPPC

C-type natriuretic peptide

NPPC

Molecular Synopsis