FEATURES

FAMILY

DESCRIPTION

Also known as NK1R_HUMAN, TACR1, NK1R, TAC1R. This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K. Interacts with ARRB1.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

TACR1

Substance-P receptor

TACR1

Molecular Synopsis