FEATURES

FAMILY

DESCRIPTION

Also known as CD38_HUMAN, CD38. Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CD38

ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1

CD38

Molecular Synopsis