FEATURES

FAMILY

DESCRIPTION

Also known as AL4A1_HUMAN, ALDH4A1, ALDH4, P5CDH. Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes. Homodimer.

Also known as AL4A1_HUMAN, ALDH4A1, ALDH4, P5CDH. Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary ste ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ALDH4A1

Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

ALDH4A1

Molecular Synopsis