FEATURES

FAMILY

DESCRIPTION

Also known as PE2R1_HUMAN, PTGER1. Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PTGER1

Prostaglandin E2 receptor EP1 subtype

PTGER1

Molecular Synopsis