FEATURES

DESCRIPTION

Also known as FHR2_HUMAN, CFHR2, CFHL2, FHR2, HFL3. Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism. Head-to-tail homodimer and heterodimer with CFHR1 or CFHR5.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CFHR2

Complement factor H-related protein 2

CFHR2

Molecular Synopsis