FEATURES

FAMILY

CDKN2 cyclin-dependent kinase inhibitor family

DESCRIPTION

Also known as CDN2C_HUMAN, CDKN2C, CDKN6. Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB. Heterodimer of p18 with CDK6.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CDKN2C

Cyclin-dependent kinase 4 inhibitor C

CDKN2C

Molecular Synopsis