FEATURES

FAMILY

DESCRIPTION

Also known as AL3B1_HUMAN, ALDH3B1, ALDH7. Oxidizes medium and long chain saturated and unsaturated aldehydes (PubMed:17382292, PubMed:23721920). Metabolizes also benzaldehyde (PubMed:17382292). Low activity towards acetaldehyde and 3, 4-dihydroxyphenylacetaldehyde (PubMed:17382292, PubMed:23721920). May not metabolize short chain aldehydes. Can use both NADP(+) and NAD(+) as electron acceptor (PubMed:17382292). May have a protective role against the cytotoxicity induced by lipid peroxidation (PubMed:17382292).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ALDH3B1

Aldehyde dehydrogenase family 3 member B1

ALDH3B1

Molecular Synopsis