FEATURES

FAMILY

DESCRIPTION

Also known as CDN1C_HUMAN, CDKN1C, KIP2. Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life. Interacts with PCNA.

Also known as CDN1C_HUMAN, CDKN1C, KIP2. Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitoti ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CDKN1C

Cyclin-dependent kinase inhibitor 1C

CDKN1C

Molecular Synopsis