FEATURES

FAMILY

DESCRIPTION

Also known as FGF12_HUMAN, FGF12, FGF12B, FHF1. Involved in nervous system development and function. Involved in the positive regulation of voltage-gated sodium channel activity. Promotes neuronal excitability by elevating the voltage dependence of neuronal sodium channel SCN8A fast inactivation. Interacts with the C-terminal region of SCN9A.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

FGF12

Fibroblast growth factor 12

FGF12

Molecular Synopsis