FEATURES

DESCRIPTION

Also known as CNBP_HUMAN, CNBP, RNF163, ZNF9. Single-stranded DNA-binding protein that preferentially binds to the sterol regulatory element (SRE) sequence 5'-GTGCGGTG-3', and thereby mediates transcriptional repression (PubMed:2562787). Has a role as transactivator of the Myc promoter (By similarity). Binds single-stranded RNA in a sequence-specific manner (By similarity)., Binds G-rich elements in target mRNA coding sequences (PubMed:28329689). Prevents G-quadruplex structure formation in vitro, suggesting a role in supporting translation by resolving stable structures on mRNAs (PubMed:28329689)., Binds to RNA., Binds to RNA., Binds to RNA., Binds to RNA., Binds to RNA. Associates with the 40S ribosomal subunit, the 80S ribosome and with polysomes.

EXTERNAL LINKS

CNBP

CCHC-type zinc finger nucleic acid binding protein

CNBP

Molecular Synopsis