FEATURES

FAMILY

ligand-gated ion channel (TC 1.A.9) family

DESCRIPTION

Also known as GBRE_HUMAN, GABRE. GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Generally pentameric. Associates with alpha and beta subunits.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

GABRE

Gamma-aminobutyric acid receptor subunit epsilon

GABRE

Molecular Synopsis