FEATURES

FAMILY

cyclic nucleotide phosphodiesterase family

DESCRIPTION

Also known as PDE1B_HUMAN, PDE1B, PDES1B. Cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes (PubMed:8855339, PubMed:9419816, PubMed:15260978). Has a preference for cGMP as a substrate (PubMed:9419816). Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PDE1B

Dual specificity calcium/calmodulin-dependent 3', 5'-cyclic nucleotide phosphodiesterase 1B

PDE1B

Molecular Synopsis