FEATURES

DESCRIPTION

Also known as FHR1_HUMAN, CFHR1, CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, HFL1, HFL2. Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism. Head-to-tail homodimer and heterodimer with CFHR2 or CFHR5.

Also known as FHR1_HUMAN, CFHR1, CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, HFL1, HFL2. Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and ef ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CFHR1

Complement factor H-related protein 1

CFHR1

Molecular Synopsis