FEATURES

FAMILY

DESCRIPTION

Also known as DUS2_HUMAN, DUSP2, PAC1. Dephosphorylates both phosphorylated Thr and Tyr residues in MAPK1, and dephosphorylation of phosphotyrosine is slightly faster than that of phosphothreonine (PubMed:8107850). Can dephosphorylate MAPK1 (By similarity). Interacts with MAPK14; this interaction does not lead to catalytic activation of DUSP2 and dephosphrylation of MAPK14.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

DUSP2

Dual specificity protein phosphatase 2

DUSP2

Molecular Synopsis