FEATURES

DESCRIPTION

Also known as TBL3_HUMAN, TBL3, SAZD. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Part of the small subunit (SSU) processome, composed of more than 70 proteins and the RNA chaperone small nucleolar RNA (snoRNA) U3.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

TBL3

Transducin beta-like protein 3

TBL3

Molecular Synopsis